Characterization of Acid-sensing Ion Channels in Dorsal Horn Neurons of Rat Spinal Cord*□S
نویسندگان
چکیده
From the ‡Institute of Neuroscience, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, §School of Life Sciences, University of Science and Technology of China, Hefei 230027, ¶Department of Pharmacology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China, Department of Physiology, University of Toronto, Toronto, Ontario M5S 1A1, Canada, and **Laboratory of Learning and Memory, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China
منابع مشابه
Characterization of acid-sensing ion channels in dorsal horn neurons of rat spinal cord.
Acid-sensing ion channels (ASICs) are ligand-gated cation channels activated by extracellular protons. In periphery, they contribute to sensory transmission, including that of nociception and pain. Here we characterized ASIC-like currents in dorsal horn neurons of the rat spinal cord and their functional modulation in pathological conditions. Reverse transcriptase-nested PCR and Western blottin...
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